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Active Ingredients of FOX04-DRI (Proxofim) Anti-Aging & Longevity, Targeted Senolytic Action Peptide The active component is FOX04-DRI (FOXO4-DRI), a synthetic peptide engineered to mimic a region involved in FOXO4 binding, with modifications intended to improve cellular uptake and functional disruption of the FOXO4p53 interaction
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3.2.7 Other PD-related genes/proteins potentially associated with ferroptosis The absence of CISD1, an iron-rich outer mitochondrial membrane protein, triggers mitochondrial dysfunction alongside the depletion of striatal dopamine and TH, thus facilitating the advancement of PD and the worsening of its clinical manifestations (172)
R., Moran, T
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