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The biological target of FOXO4-DRI is the FOXO4p53 protein-protein interaction a molecular axis identified as pivotal for maintaining the viability of senescent cells

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This finding provides an important theoretical basis for the development of tumor immunotherapy strategies based on the regulation of ferroptosis timing, especially in terms of optimizing the ICD process to enhance antitumor immune responses

Echaubard P, Len T, Suwanatrai K, Chaiyos J, Kim CS, Mallory FF, Kaewkes S, Spear RC, Sripa B

Vyroubal, P