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Specifically, FXR interacts with CRTC2, preventing its association with CREB at ATG promoters, thereby inhibiting the transcription of genes required for autophagosome initiation and lysosomal biogenesis
Likewise, micronutrients such as zinc (Zn), copper (Cu), and manganese (Mn), key cofactors of antioxidant enzymes, become critical for maintaining redox balance under elevated ROS pressure
This article was medically reviewed by Renae Thomas, MD, MPH
The Science-Backed Benefits of Glutathione Glutathione is your bodys frontline defence against oxidative stressthe cellular wear and tear that accelerates aging and leaves you vulnerable to illness