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While the exact mechanisms are still being studied, this suggests the glucagon component may play a key role in counteracting metabolic slowdown and fatigue, making Reta especially interesting in long-term metabolic research

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Peptide-based GLP-1/glucagon co-agonists: a double-edged sword to combat diabesity

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Second, as a stimulant, long-term use is generally avoided to prevent potential strain on the cardiovascular system and to minimize the risk of dependency

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Also worth keeping in mind: Wegovy, like other GLP-1s, isn't a one-and-done drug that you stop taking once you lose weight

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