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Moreover, tumor-derived exosomes are able to promote cancer cell migration and metastasis, containing various kinds of integrin, such as exosomal integrins v 6 for prostate cancer (Carmine et al., 2015), 6 4 and 6 1 for lung cancer, and v 5 for liver cancer metastasis (Hoshino et al., 2015)

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Besides, EC has displayed neuroprotective potential by the decreased in A-induced apoptosis that is partially related to the p38 MAPK and JNK pathways activation (Ramiro-puig et al., 2009

In addition to sunburn and tanning, prolonged exposure to the sun without protection can cause freckles, dark patches, and uneven skin tone