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Gene ontology categorization analysis indicated that many proteins involved in the electron transport and oxidation-reduction process were down-regulated in expression after riboflavin deficiency, including AOFB, DLD, NQO1, NDUFS1, AK1C2, AIFM1, SDHA, TRXR1, AK1C3, DERP12, MCAD, PLOD2, SRXN1, PLCA, NDUFV2, and ERO1A
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Jaime Almandoz, medical director of UT Southwestern Medical Centers Weight Wellness Program, said in a news release
In vivo study showed that UA can induce autophagy, the primary process for clearing intraneuronal aggregated -synuclein, by inhibiting mTOR/ULK1 signaling in the midbrain of SNCA A53T transgenic mice
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