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On the other hand, obesity is also characterized with increased UA levels

Inhibition of cytokine receptor synthesis and blockade of the autocrine and paracrine actions of cytokines and PGE 2 were also observed

In addition, some inducers of these enzymes affect phase I detoxification enzymes, which frequently may transform procarcinogens to actual carcinogens via metabolic activation by hydroxylases such as cytochrome P450

The use of food dyes is at least controversial because they are only of essential role

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