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I still do maintenance cycles every few months now

Mutants that have a low ascorbate content have significant reprogramming of gene expression, including genes involved in hormone synthesis and signalling, as well as photosynthesis and defence (Kiddle et al

10.1016/j.envint.2021.107015 Environ Int

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FA-97 activates Nrf2 and promotes its nuclear translocation to increase expression of its downstream target proteins HO-1 and NAD(P)H:quinone oxidoreductase (NQO-1), which reduces ROS