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Cagrilintide Storage & Handling Cagrilintide Storage Reference State Lyophilized (powder) Storage -4F (-20C) freezer Duration Up to 24 months State Lyophilized (short-term) Storage 35.6-46.4F (2-8C) refrigerator Duration Acceptable for shipping or short storage State Reconstituted (liquid) Storage 35.6-46.4F (2-8C) refrigerator Duration 28-30 days

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Freezing and filtration produced proteins of 14 and 16 kDa with coagulation activity (Martha et al

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Instrumentation Agilent 1290 Infinity II UHPLC system, including high-speed pump, multisampler with thermostat, multicolumn thermostat, diode array detector, coupled to Agilent 6545XT AdvanceBio LC/Q-TOF