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La historia detrs de la revolucin de los agonistas de receptores GLP-1 #diabetesjlcolina GLP-1 para el Tratamiento de la Obesidad: Origen, Historia y Evolucin El reconocimiento de los agonistas del receptor del pptido similar al glucagn-1 (GLP-1RAs) como tratamiento fundamental en el manejo de la obesidad representa uno de los avances ms significativos en la medicina metablica, culminando con el Premio Lasker-DeBakey de Investigacin Mdica Clnica 2024

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Under cholesterol stimulation, GLP-1-induced AMPK activation inhibited PARP-1 activity, therefore attenuating cholesterol-induced toxicity in INS-1 cells