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Mutant huntingtin (mHTT) induces metabolic and cellular stress through impaired insulin signaling, defective autophagy, mitochondrial dysfunction, oxidative stress, and synaptic loss (171), processes that overlap with pathways modulated by GLP-1RAs

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It has been suggested that the disease occurrence is usually associated with radiation or neurofibromatosis type 1 (NF-1)

Bilirubin inhibits neointima formation and vascular smooth muscle cell proliferation and migration

A 4-week crossover study examined the effects of CIT supplementation (6 g/day) on microvascular function and muscle strength in 16 middle-aged and older adults with type 2 diabetes