Psychol Med 33(3):395405 Correia AS, Cardoso A, Vale N (2023) Oxidative stress in depression: the link with the stress response, neuroinflammation, serotonin, neurogenesis and synaptic plasticity
In summary, System X c /GSH/GPX4 axis-based ferroptosis may be a research direction for reversing drug resistance and may provide a rational basis for the development of new therapies for drug resistant solid tumors
Cautions NAC should be used with caution in patients with current or a history of gastrointestinal ulceration, bronchial asthma, liver and kidney failure
Silencing GPX3 expression promotes tumor metastasis in human thyroid cancer
BSO-sensitive cells (G402, RCC4 VHL/, and A-498) tended to exhibit lower glutathione levels (P=0.08) compared with those of insensitive cells (RCC4 VHL+/+, Caki-2, and HCT-116) (Fig