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Stage 2 skin is uneven with indentations (like cellulite) representing thickening and contraction of underlying connective tissue fibers over increased fat with small to larger hypodermal masses

And calorie restriction in non-obese populations can improve metabolic health by reducing energy intake (e.g., 25%), manifesting as weight loss, enhanced insulin sensitivity, decreased cardiovascular risk factors (such as blood lipids and blood pressure), and activation of aging-related molecular pathways (e.g., enhanced mitochondrial function and DNA repair) [19]

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When combined with complementary treatments, they enhance the efficacy and help you extend both your life span and health span (the years you live free of disease or chronic conditions)

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