In a mouse model of MI, an antibody against glucagon improved cardiac function and ameliorated the progression of HF by blunting cardiac hypertrophy, fibrotic remodeling, and attenuated contractile dysfunction at 4 weeks after MI (Gao et al
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In animals with induced liver damage, KEDA administration normalized immune status, improved antioxidant defenses, and restored various markers of liver function
While many people anticipate digestive changes when starting a GLP-1 medication, some experience a more unusual sensation: skin that feels tender, tingly, or overly sensitive to the touch
Here's the quick version: For a 10mg vial: Add 2mL of bacteriostatic water (BAC water) this gives you 5mg/mL For a 0.25mg dose: draw 5 units (0.05mL) on a U-100 insulin syringe For a 0.5mg dose: draw 10 units For a 1mg dose: draw 20 units For a 20mg vial: Add 4mL BAC water same 5mg/mL concentration, same dose math above Injection technique: SubQ injection pinch the skin at belly, thigh, or upper arm 31g or 32g insulin needle ( inch length is fine for subQ) Inject slowly, hold for 5 seconds before withdrawing Refrigerate after reconstitution stable 4-6 weeks in the fridge Realistic Expectations for Weeks 1-12 Here's what most people experience on a conservative titration, assuming reasonable diet and some exercise: Weeks 1-2: Minimal weight change
