[4] In case of accidental large overdose (e.g., someone receives far more frequent injections than prescribed), monitoring for symptoms like flushing, tingling in extremities, or liver enzyme elevations would be prudent
Therefore, while efforts undoubtedly need to be intensified towards preventing the onset of the disease and making lifestyle modifications (a fundamental aspect of the therapy for every patient with T2DM), it is clear, as indicated by the most recent guidelines [78], that the pharmacological approach should focus on timely treatment that leaves no room for therapeutic inertia and employs medications that are as effective as possible in both metabolic control and the prevention of chronic complications
As shown in the schematic overview of the experimental set-up (Fig
Serrano-Pozo A, Frosch MP, Masliah E, Hyman BT
Our guide to reading peptide CoA documents explains how to interpret both types of analytical data in detail