semaglutide ophthalmology The obesity drug (Wegovy) conferred a significantly higher risk of ischemic optic neuropathy (ION) than any other GLP-1 agonist, including semaglutide for diabetes (Ozempic), an analysis of FDA data showed. Added Our vitreoretinal surgeon explains what

These include certain antipsychotics (olanzapine, quetiapine, risperidone), mood stabilizers (lithium, valproate), some antidepressants (mirtazapine, paroxetine, amitriptyline), corticosteroids (prednisone), certain diabetes medications (insulin, sulfonylureas, thiazolidinediones), some beta-blockers (propranolol, metoprolol), and anticonvulsants (gabapentin, pregabalin)

Thyroid C-cell warning: Rodent C-cell tumor findings underlie the labeled MTC/MEN-2 caution for approved GLP-1 drugs (human relevance uncertain), and it carries over to the semaglutide arm

Some patients benefit from anti-nausea medications like ondansetron used short-term, or from adjusting injection timing

Side Effects: Both combinations are generally well-tolerated, but individual experiences can vary

C., Patel, R