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Saxenda (Liraglutide) FDA approval: 2014 for chronic weight management Indicated population: Adults with BMI 30, OR Adults with BMI 27 with at least one weight-related condition Also available as: Victoza (lower dose, approved for Type 2 diabetes) Ozempic (Semaglutide) FDA approval: 2017 for Type 2 diabetes Indicated population: Adults with Type 2 diabetes as adjunct to diet and exercise Not approved for: Weight loss (though commonly prescribed off-label) Wegovy (Semaglutide) FDA approval: 2021 for chronic weight management Indicated population: Adults with BMI 30, OR Adults with BMI 27 with at least one weight-related condition Adolescents aged 12+ with obesity Same medication as Ozempic: Different dosing and FDA indication Practical Implications The regulatory distinctions matter for: Insurance coverage: Medications are often covered only for their approved indications

[64] Dietary recommendations [edit] Some research shows that most people in the United States and the United Kingdom consume sufficient vitamin B 12

Ozempic and metformin have been shown to promote weight loss as a side effect

Topical forms of HRT, such as oestrogen gels or suppositories, are often preferred as their absorption is not affected by gastric emptying

Many patients also see improvements in blood pressure, cholesterol, blood sugar, and insulin resistance