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Having more than that overloads your system with more booze than it can process at once, which is what ultimately causes you to feel drunk and sends your BAC over the legal limit.

J Intern Med 257:299310, PMID: 15715687 Bested AC, Saunders PR, Logan AC (2001) Chronic fatigue syndrome: neurological findings may be related to bloodbrain barrier permeability

Harackiewicz O, Grembecka B (2024) The role of microglia and astrocytes in the pathomechanism of neuroinflammation in Parkinsons disease-focus on alpha-synuclein

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Genetic factors and concurrent life stressors significantly influence risk