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Work by Culhane et al

Frontiers in Aging Neuroscience, 8 , 276.

[DOI] [PubMed] [Google Scholar] 10.Sonigo C, et al

Epigenetic mechanisms may also be involved in the development of migraine, and understanding environmentally induced genetic changes associated with this disease may eventually guide the development of therapies capable of reversing these pathophysiological changes in gene function

An absolute HT rate for each stroke phase is difficult to establish considering the multitude of factors influencing its development, but it seems clear that recanalization occurring after the hyperacute phase is directly linked with the early appearance of HT, while the lack of recanalization may motivate a delayed appearance of HT