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6.6.1 Ovarian cancer (OC) OC is the primary cause of mortality among females who receive a diagnosis of gynecological cancer (Menon et al., 2021)

(148) investigated the effects of -LA supplementation on migraine through a clinical trial

10.3389/fimmu.2025.1577234 101 WipplingerA.BekricD.AblingerC.KittlM.MayrC.RitterM.et al (2025)

Diabetes mellitus and vascular complications Patients with diabetes mellitus have been reported to have low plasma concentrations and high renal clearance of thiamin (40, 41), suggesting that individuals with type 1 or type 2 diabetes are at increased risk for thiamin deficiency

In addition to the aforementioned case studies, we have published analysis of ascorbate pharmacokinetics (plasma concentration rise and fall after infusion) and a Phase I clinical study