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Patients with severe renal or hepatic impairment require careful assessment and specialist input before treatment initiation

Patients are initiated at 30 mg/dose (equivalent to 0.82 mol GLP-1 RA per dose) and can be increased to 50 mg/dose (1.37 mol/dose) if necessary (Table 1) [23]

It cant be manufactured by your body, so if your diet is lacking, youre going to notice