Antifibrotic response in aged mice The incidence of IPF is positively correlated with aging and is more prevalent among the elderly population 2
But risks exist: improper use (high doses, unregulated supplements) may cause nausea, serotonin syndrome (with certain drugs), or nerve damage
Many argue that it shouldnt fall under doping classifications
These responses elevate the synthesis of superoxide dismutase (SOD), catalase, as well as key molecules like nicotinamide adenine dinucleotide phosphate (NADPH) and glutathione (GSH), thereby maintaining cellular redox homeostasis
Their muscle-to-fat ratio usually still improves, but in particularly vulnerable populations, such as older adults, rapid and significant muscle loss can be a dangerous issue