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Kaufman noted that its possible that starting at 2.5mg might work its just that no one has tried

These effects contribute to its potential in mitigating key mechanisms underlying cardiovascular diseases (CVDs), such as oxidative stress, endothelial dysfunction, and inflammation

This was an unexpected result insofar that GPX3 is considered a classical Nrf2-induced gene and TNF- has repeatedly been reported to upregulate other Nrf2 target genes in various cell types including leukocytes of the myeloid lineage, vascular endothelial cells, and osteoblasts 50,51,52,53,54

CHRIS MASTERJOHN: It makes complete sense

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