They concluded that the esterified GSH derivative was effective in reducing melanin and tyrosinase activity and raised the pheomelanin/eumelanin ratio without affecting cellular viability
On the other, it may interfere with certain stages of melanin synthesis, including the activity of tyrosinase, an enzyme involved in pigment production
Lu H, Fan L, Zhang W, et al
10 Many efforts have been made in response to each process of the drug transportation, which have also been accompanied by reviews of latest progress in this field, but most of literature emphasize the BBB breakdown in specific brain disorders, 11,12,13,14 or give a general review of delivery strategies concentrating on the barrier physiology
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