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NOX-B11, a high-affinity Spiegelmer specific for octanoylated ghrelin, reduces ghrelin-induced food intake 90 and leads to weight loss in mice with diet-induced obesity

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The mice were housed in micro-isolator cages under a 12-h light/dark cycle with free access to food and water, in compliance with protocols reviewed and approved by the Institutional Animal Care and Use Committee of Keimyung University (KM2023-017)

This suggests BPC-157 could potentially improve benzodiazepine efficacy during chronic treatment and ease withdrawal, but no human studies have tested this

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