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Xiang, Q

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Supplementary Figs 57), a valuable and well established approach in modelling human neurological disorders in vitro 22,27

These data support an effect of IL-13 to decrease total and reduced GSH through high 15LO1, PEBP1, and GPX4 activity, which is partially compensated by (a) increased expression/activity of SLC7A11 to enhance new intracellular GSH production and (b) increased export of GSSG