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We carried out metabolomics study based on a combination of DBS sampling and MS technology to systematically define metabolic profiles for patients with AHU and gout toward detected amino acids, carnitine/acylarinieint, and their ratios

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In order to improve fiber intake during a caloric deficit with reduced appetite, prioritizing the highest-fiber food sources (avocado, chia seeds, pears, berries, legumes) alongside fiber supplementation will help to mitigate the constipation experienced with GLP-1 agonists while supporting the therapeutic goal of satiety and blood glucose regulation

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The most common comorbidity in the Wegovy cohort was depression (21.83% vs