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J Physiol Paris , 1998, 92(3-4): 289-292

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Having demonstrated that GLP-1MK-801 and GLP-1inactive MK-801 display comparable pharmacokinetic properties in vitro, we next assessed their respective in vivo efficacies against the parent GLP-1 analogue in DIO mice

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During the conversion of isocitrate to -KG, Idh1 catalyzed the generation of NADPH, and NADPH and reduced nicotinamide adenine dinucleotide (NADH) were reductants for lipid biosynthesis and antioxidants that protect cells from oxidative stress and radiation damage [77]

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