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Post-treatment with PT302, a long-acting Exendin-4 sustained release formulation, reduces dopaminergic neurodegeneration in a 6-hydroxydopamine rat model of Parkinsons disease

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However, a trial involving 40 Hispanic women with moderate to severe melasma using sunscreen and randomized to receive oral placebo or 720 mg PL extract daily for 12 weeks revealed no difference in MASI reduction [90]