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Variations in these genes can cause EDS: [9] Collagen primary structure and collagen processing: ADAMTS2 , COL1A1 , COL1A2 , COL3A1 , COL5A1 , COL5A2 Collagen folding and collagen cross-linking: PLOD1 , FKBP14 Structure and function of myomatrix: TNXB , COL12A1 Glycosaminoglycan biosynthesis: B4GALT7 , B3GALT6 , CHST14 , DSE Complement pathway: C1R , C1S Intracellular processes: SLC39A13 , ZNF469 , PRDM5 Variations in these genes usually alter the structure, production, or processing of collagen or proteins that interact with collagen

If you do, you will probably need to go back to step one

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Colonne, Stock, 2022

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