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Ethics statement The studies involving humans were approved by The Ethics Review Board of Shin-Kong Wu Ho-Su Memorial Hospital (IRB number: 20250104R)

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16S rRNA gene sequence analysis Fecal samples were harvested from each mouse through abdominal pressing and collected in sterilized tubes

Figure 3 GJA or pouch conversion can be performed by either reshaping these structures or by removing part of the GJA followed by a reconstruction (87)