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As a result, there is growing interest in incorporating physiologic traits such as loop gain, arousal threshold, and upper airway responsiveness into assessment frameworks to better guide individualized treatment strategies

Incretins can also mobilize stored Ca 2+ in intracellular organelles by activating ryanodine (RYR) [8] and inositol 1, 4, 5-trisphosphate receptors (IP 3 R) [9]