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HFD inhibits the transcription of key antioxidant genes by triggering NRF2 translocation into obese mouse Tregs nucleus, causing a rapid decline in HO-1 expression in Tregs, leading to enhanced oxidative stress and possible ferroptosis, and causing an intensification of obesity and inflammatory responses (156) ( Figure 3 )
The metabolic mechanism formed by the above metabolites may be involved in the pathogenesis impacted by SLE
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I couldnt fight anymore. The former swimsuit model has undergone several surgeries to remove infected tissue and endures six hours of IV antibiotics daily
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