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105 HSF2 can regulate the mitochondrial phagocytosis of intestinal epithelial cells via the PARL/PINK1/Parkin pathway, removing damaged mitochondria, decreasing the levels of mtROS in cells, suppressing intestinal mucosal inflammation, and maintaining the intestinal environment balance in UC

The SURPASS trials showed tirzepatide produced greater HbA1c reductions than semaglutide at all dose levels

The peptide sequence consists of fifteen amino acids arranged as Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, forming a stable molecular structure that demonstrates resistance to enzymatic degradation compared to other peptide compounds

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