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Brain Res Rev 25:335-358 Riddle DR (2007) Brain Aging: Models, Methods, and Mechanisms
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Together, schisandrin lignans such as schisandrin A and B demonstrate broad anti-inflammatory activity through their ability to inhibit pro-inflammatory mediators, suppress critical signaling pathways such as NF-B and MAPKs, and enhance antioxidant defenses via NRF2 activation
It is naturally released into the bloodstream during times of stress
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