Emphasize smoking cessation Manage BP, lipids using diabetes thresholds Screen for diabetes Encourage maintenance of healthy weight Slightly higher risk of overall cancer development Emphasize need for malignancy screening, especially cervical and colorectal cancer Discuss reproductive health Assess bone health Risk of vitamin D deficiency due to sun avoidance and decreased bone density from glucocorticoid use and inflammation Assess mental health Anxiety and depression is commonly seen in patients with lupus
For patients who want triple-agonist therapy now, there is no FDA-approved option
Furthermore, GLP-1s do not typically cause hypoglycemia unless used in combination with sulfonylureas or insulin
By contrast, glucagon-like peptide-1 agonist (GLP-1A) has shown a strong glucose-dependent hypoglycemic effect with few cardiovascular-related side effects, resulting in a significant market share [3,4,5]
Searches for "ozempic sun sensitivity" have climbed, but the results are split between overstatement and dismissal