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10.1007/s00406-004-0456-7 21

Ipamorelin acts on the ghrelin receptor (GHSR-1a) while CJC 1295 acts on GHRHR

However, GLP-1s also offer well-established research with fewer gastrointestinal side effects

Researchers can use this data to optimize COA design or selection regardless of modality, target demographic, or indication, with potential positive effects on comparability, translatability, data quality, and the patient experience, as COAs and expectations about them converge on more straightforward and familiar structures and language