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Sodium-glucose cotransporter 2 (SGLT2) inhibitors have demonstrated both kidney- and heart-protective effects in individuals with CKD, and other agents, such as non-steroidal mineralocorticoid receptor antagonists (ns-MRA), provide cardio-kidney protection in patients with diabetes and kidney disease

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Anyone with systemic or respiratory symptoms should be evaluated promptly and managed by experienced clinicians

Patients are often paying out of pocket anyway

However, patients using additional diabetes medications should monitor blood glucose carefully and may require dose adjustments of other agents