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Remarkably, increasing evidence also points toward GPX4 protein degradation as a means to incite cancer cell ferroptosis and apoptosis in hepatocellular carcinoma and breast cancer cells [221,222,223]

Complementary approaches like surface charge neutralization, PEGylation modifications, or Fc-region fusion could further enhance serum half-life while mitigating ADA responses 36,37

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This side effect is pretty common and usually goes away on its own