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Evidence for the necessity to systematically assess micronutrient status prior to bariatric surgery

In such systems, the ascorbateglutathione cycle, together with TRXs, PRXs, glutaredoxins (GRXs), and antioxidant enzymes, such as superoxide dismutase (SOD) and catalase (CAT), ensures appropriate redox-mediated regulation, so that ROS, ascorbate, and glutathione can accumulate in the required compartment-specific manner

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The second hit involves progressive hepatic injury, contributing to conditions such as steatohepatitis, advanced fibrosis, and cirrhosis [20]

The third mouse model involves bone-marrow-derived macrophages, primary cells isolated directly from mouse bone marrow