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Fondriest also acknowledges lithiums efficacy, stating, Lithium has unparalleled power in stabilizing bipolar disorder, but he remains cautious about potential long-term kidney and thyroid risks, especially in younger patients

Yet, existing and ongoing research is continuing to show a deleterious relationship

Gastrointestinal side effects have been the most prominent concern in danuglipron trials and are common across the GLP-1 class

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