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hdl:10665/42716

Bedrosian highlights a study demonstrating that the positive impact on kidney function is independent of weight loss, suggesting a direct protective effect of the drug

Cagrilintide combinations The emerging cagrilintide and tirzepatide combination represents a different approach to multi-receptor targeting

DUAL GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE/GLUCAGON-LIKE PEPTIDE-1 RECEPTOR CO-AGONISTS In 2015, following the success of dual GIP/GLP-1 receptor co-agonists, the first triple GLP-1/GIP/glucagon receptor triagonist was developed with the rationale that the synergistic effect of the three gastrointestinal hormones will achieve further efficacy compared to the dual gastrointestinal hormone approach [58]

It is being tested to treat obesity and type 2 diabetes by itself and in combination with semaglutide as cagrilintide/semaglutide ("CagriSema")