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Its hallmark manifestations include progressive cognitive decline, memory loss, and central/peripheral nervous system dysfunction

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The trial randomized 3,127 participants across the U.S., Brazil, China, India, Japan, South Korea, Puerto Rico, Slovakia, Spain and Taiwan to receive various doses of orforglipron or placebo along with healthy diet and physical activity

Tirzepatide: A Novel, Once-weekly Dual GIP and GLP-1 Receptor Agonist for the Treatment of Type 2 Diabetes. TouchREVIEWS in Endocrinology 18 no.1 (2022): 10-19