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Key trials include a 2017 phase 2 study of exenatide showing modest motor improvements, and the 2024 LIXIPARK study demonstrating lixisenatide benefits on motor function

About the Study The present study aimed to bridge this knowledge gap and inform future psychiatric research and clinical policy by leveraging a frequentist network meta-analysis with a random-effects model to simultaneously elucidate the safety and efficacy of multiple distinct GLP-1 RA regimens

Decreased butyrate production is also associated with elevated oxygen levels in the intestinal mucosa, increasing the risk of oxidative damage [150]