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Insoluble fiber adds bulk to the stool and helps the contents of the digestive tract move more quickly, which makes it a helpful tool in preventing or treating constipation

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Obesity promotes a chronic, low-grade inflammatory state through adipokine release and up-regulation of cytokines such as tumor necrosis factor (TNF), interleukin-17 (IL-17), and IL-6, while mechanical stress at entheseal sites and reduced physical activity exacerbate musculoskeletal symptoms