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According to FDA prescribing information, nausea occurs in 1544% of patients depending on the specific agent and dose, with vomiting, diarrhea, constipation, and abdominal pain also frequently reported

In contrast, Ex-4 has exhibited significant anti-tumor proliferation effects within a concentration range of 0.5 to 10 nM

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4 Unfortunately, the general but insurmountable problem is that neither of the supposed mediators when applied as a therapy could realize in practice the full theoretical assumption that homeostasis could be achieved

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