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If corticosteroids are used, basal insulin may not be sufficient

GLP-1 (glucagon-like peptide-1) receptor agonists, such as semaglutide and liraglutide, were originally developed to treat type 2 diabetes but have also shown strong effectiveness in managing obesity and supporting weight loss

Patients should expect their tolerance for food volume to fluctuate during these adjustments, with gradual stabilization as the body adapts to each new dose level

In some cases, switching to a different GLP-1 receptor agonist or alternative diabetes or weight management therapy may be recommended

The right response is not to dismiss that possibility, but to insist on the blinded, placebo-controlled human trials that could actually settle the question