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Initial concerns about the relationship between GLP-1 receptor agonists and pancreatitis emerged from early preclinical studies and post-marketing reports, which suggested an increased incidence of pancreatitis among users of this class of medications

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Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications originally developed for managing type 2 diabetes, though some are now also licensed for weight management

Most symptoms improve with dose adjustments

We also determined whether the Western diet might aggravate gluconeogenesis by performing the pyruvate tolerance test