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The formulation components, injection technique, or individual tissue sensitivity may contribute to localized itching, erythema, or irritation

Nausea, vomiting, constipation, and diarrhea hit 40-50% of patients during dose escalation per STEP and SURMOUNT safety profiles

The brand-name developer, Eli Lilly, is currently running the Phase 3 TRIUMPH clinical trial program

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The medications are approved for long term use if desired