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doi: 10.1007/s00125-007-0681-5 13 ZhaoHWangLWeiRXiuDTaoMKeJet al

Additionally, GLP-1 receptor agonists act on appetite-regulating centers in the hypothalamus, reducing hunger signals and promoting weight loss

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These agents reduce the amount of proinflammatory cytokines, such as interleukin (IL) 17A and tumor necrosis factor- (TNF-) that play a role in keratinocyte hyperproliferation and the inflammation that characterizes psoriatic plaques

Research consistently shows that people on GLP-1 medications who don't prioritize protein lose significant amounts of muscle along with fat studies suggest up to 40% of weight lost can be lean muscle mass